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Those with chronic Hepatitis C become susceptible to HE when a heavily damaged liver is unable to filter toxins from the blood or when blood flow through the liver is blocked. Although few individuals with Hepatitis C develop full-blown hepatic encephalopathy, some degree of brain impairment may occur in as many as three-quarters of those who have advanced liver cirrhosis.
The severity of hepatic encephalopathy is measured on a five-point scale:

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